2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-101577
    NCX899 690655-41-5 98%
    NCX899 is a NO-releasing derivative of enalapril, and shows inhibitory activity against angiotensin-converting enzyme (ACE) activity.
    NCX899
  • HY-101594
    Tulopafant 116289-53-3 98%
    Tulopafant is a platelet activating factor (PAF) antagonist.
    Tulopafant
  • HY-101598
    PD-159020 177904-00-6 98%
    PD-159020 is a non-selective ETA/ETB antagonist, with IC50s of 30 and 50 nM for hETA and hETB, respectively.
    PD-159020
  • HY-101617
    Droxicainide 78289-26-6 98%
    Droxicainide is an antiarrhythmic agent.
    Droxicainide
  • HY-101618
    L162389 169281-53-2 99.57%
    L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.
    L162389
  • HY-101661
    Win 58237 158001-76-4 98%
    Win 58237 is a cyclic nucleotide phosphodiesterase (PDE) inhibitor, with Ki of 170 nM for PDE V, possessing vasorelaxant activity.
    Win 58237
  • HY-101668
    Sulamserod 219757-90-1 98%
    Sulamserod is a 5-HT4 receptor antagonist, with antiarrhythmic activities.
    Sulamserod
  • HY-101674
    Tiapamil hydrochloride 57010-32-9 98%
    Tiapamil hydrochloride is a calcium channel blocker.
    Tiapamil hydrochloride
  • HY-101681
    Utibapril 109683-61-6 98%
    Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activities.
    Utibapril
  • HY-101685
    Iganidipine 119687-33-1 98%
    Iganidipine is a Ca2+ antagonist.
    Iganidipine
  • HY-101691
    Ecastolol 77695-52-4 98%
    Ecastolol is a beta adrenergic receptor antagonist, with antianginal activities.
    Ecastolol
  • HY-101700
    LCB-2853 141335-10-6 98%
    LCB-2853 is an antagonist of thromboxane A2 (TXA2) receptor, with antiplatelet and antithrombotic activities.
    LCB-2853
  • HY-101706
    CGP48369 135689-23-5 98%
    CGP48369 is a nonpeptidic angiotensin II receptor antagonist, used for anti-hypertensive research.
    CGP48369
  • HY-101720
    Fradafiban 148396-36-5 98%
    Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.
    Fradafiban
  • HY-101721
    Ko-3290 79848-61-6 98%
    Ko-3290 is an antagonist of β-adrenoceptor, with cardioselectivity and antilipolytic effects in animals. Ko-3290 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Ko-3290
  • HY-101727
    Nexopamil racemate 116759-35-4 98%
    Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on thrombus formation in vivo and on platelet aggregation in vitro.
    Nexopamil racemate
  • HY-101733
    Zabicipril hydrochloride 90130-77-1 98%
    Zabicipril hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor. Zabicipril hydrochloride can be used for the study of blood pressure and peripheral arterial insufficiency.
    Zabicipril hydrochloride
  • HY-101775
    9-Hydroxyellipticin 51131-85-2 98%
    9-hydroxyellipticine is an inhibitor of Topo II and RyR, exhibiting high affinity for DNA with a Pka value of 9.8 at pH 7.4. It has antitumor, antioxidant, and catecholamine-releasing activities, with IC50 values of 1.6 μM and 1.2 μM for Hela S-3 and 293T cells, respectively. It also demonstrates anticancer effects in L1210 leukemia mice.
    9-Hydroxyellipticin
  • HY-101804
    (E)-Alprenoxime 125720-84-5 98%
    (E)-Alprenoxime is the isomer of the Alprenoxime. Alprenoxime is a site-activated ocular β-blocker.
    (E)-Alprenoxime
  • HY-101807
    Ro-15-2041 77448-87-4 98%
    Ro 15-2041 is a selective platelet phosphodiesterase inhibitor with antithrombotic properties.
    Ro-15-2041
Cat. No. Product Name / Synonyms Application Reactivity